KEGG   Aspergillus fumigatus: AFUA_4G06890
Entry
AFUA_4G06890      CDS       T01017                                 
Name
(RefSeq) 14-alpha sterol demethylase Cyp51A
  KO
K05917  sterol 14alpha-demethylase [EC:1.14.14.154 1.14.15.36]
Organism
afm  Aspergillus fumigatus
Pathway
afm00100  Steroid biosynthesis
afm01100  Metabolic pathways
afm01110  Biosynthesis of secondary metabolites
Module
afm_M00102  Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Brite
KEGG Orthology (KO) [BR:afm00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    AFUA_4G06890
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:afm00199]
    AFUA_4G06890
Enzymes [BR:afm01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.154  sterol 14alpha-demethylase
     AFUA_4G06890
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.36  sterol 14alpha-demethylase (ferredoxin)
     AFUA_4G06890
Cytochrome P450 [BR:afm00199]
 Cytochrome P450, animal type
  CYP51 family
   AFUA_4G06890
SSDB
Motif
Pfam: p450 DUF6007
Other DBs
NCBI-GeneID: 3509526
NCBI-ProteinID: XP_752137
UniProt: Q4WNT5
Position
4:complement(1780204..1781822)
AA seq 515 aa
MVPMLWLTAYMAVAVLTAILLNVVYQLFFRLWNRTEPPMVFHWVPYLGSTISYGIDPYKF
FFACREKYGDIFTFILLGQKTTVYLGVQGNEFILNGKLKDVNAEEVYSPLTTPVFGSDVV
YDCPNSKLMEQKKFIKYGLTQSALESHVPLIEKEVLDYLRDSPNFQGSSGRVDISAAMAE
ITIFTAARALQGQEVRSKLTAEFADLYHDLDKGFTPINFMLPWAPLPHNKKRDAAHARMR
SIYVDIITQRRLDGEKDSQKSDMIWNLMNCTYKNGQQVPDKEIAHMMITLLMAGQHSSSS
ISAWIMLRLASQPKVLEELYQEQLANLGPAGPDGSLPPLQYKDLDKLPFHQHVIRETLRI
HSSIHSIMRKVKSPLPVPGTPYMIPPGRVLLASPGVTALSDEHFPNAGCWDPHRWENQAT
KEQENDKVVDYGYGAVSKGTSSPYLPFGAGRHRCIGEKFAYVNLGVILATIVRHLRLFNV
DGKKGVPETDYSSLFSGPMKPSIIGWEKRSKNTSK
NT seq 1548 nt   +upstreamnt  +downstreamnt
atggtgccgatgctatggcttacggcctacatggccgttgcggtgctgacggcaatcttg
ctcaatgttgtttatcaattattctttcggctttggaaccgaacagaaccgccaatggtc
tttcattgggtcccatatctgggtagtaccatcagttacgggattgatccctacaagttc
ttctttgcgtgcagagaaaagtatggcgatatcttcacttttatactgttgggtcaaaaa
accacagtctacctgggcgttcagggaaacgagtttattctcaacggcaagctcaaggat
gtcaatgcggaagaggtctatagtccattgacgacccccgttttcggatcggacgtggtg
tatgattgtcccaattccaagctgatggagcagaaaaagttcatcaagtacggcttgact
cagtctgcgttagagtctcatgtgccacttattgagaaggaggttttggactatctgcgc
gattcaccgaactttcaaggctcgtccggccgggtggacatctctgcggcaatggctgag
attaccatttttaccgctgctcgagccctccaaggccaggaagttcgttccaaactcacg
gctgagttcgctgacctctatcatgacctggacaagggctttactcccatcaattttatg
ctaccgtgggccccattgccgcataacaagaagcgagatgctgctcatgcgcgcatgagg
tcaatctacgttgacatcatcactcagcgccgtcttgacggtgagaaggactctcagaaa
tcagacatgatatggaacctgatgaactgcacatacaaaaacggccagcaagtgcctgat
aaagagattgcgcacatgatgataaccctgttgatggctggtcagcattcgtcttcgtcc
atcagcgcctggattatgctgagactggcctcacagccaaaagtcctcgaagagctgtat
caggaacagctggccaatcttggccccgccgggccagacggcagtcttcctccgctccag
tacaaggatcttgacaaacttcccttccatcaacatgttattcgtgaaaccttgcggatt
cactcctctattcactctatcatgcgcaaggtgaaaagccccttgcccgttcccgggacc
ccttacatgattcctcccggtcgcgtgctccttgcttcacctggagtgacagccctcagc
gacgaacacttccccaatgctgggtgctgggatccccatcgctgggagaaccaggctact
aaggagcaggagaacgacaaggttgtcgactacggttacggcgccgtctccaagggcacg
tcaagtccctatcttccgtttggtgctggccgacaccgctgcatcggcgagaaattcgct
tatgtcaaccttggtgtgattctggcgaccattgtgcgccacctgcgacttttcaacgtg
gatggaaagaaaggagtccctgaaactgactattcatccctcttttcgggccccatgaag
ccaagcatcatcggctgggagaagcggtcgaaaaacacatccaagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (3)   
   KEGG MODULE (3)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (37)   

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